The Science Behind DNALYZE TM
A deep look at the molecular innovations that enable femtogram-level porcine DNA detection with audit-ready confidence.
Engineering the Chain of Halal Certainty
Detecting porcine DNA in highly processed products, like gelatin capsules, gummies, and oils, requires more than standard PCR. It demands a workflow engineered to overcome the chemical and physical barriers that cause other tests to fail. DNALYZE TM integrates three layers of molecular innovation to deliver binary, indisputable results.
Video Gallery: NexaBiotech Innovation Podcast
Listen to expert discussions on DNALYZE TM innovation and the Halal authentication process, from sample preparation to audit-ready results.
The Inhibitor Shield Formulation
Complex food matrices are filled with PCR inhibitors, fats, polyphenols, and chemical additives that often lead to false negative results.
The Challenge: Lipids and processed additives in things like chocolates or cosmetics can block DNA amplification.
The Innovation: Our proprietary Inhibitor Shield Chemistry neutralizes these contaminants before extraction begins, keeping the reaction environment pristine for analysis.
Ultra-Capture Spin Columns
In heavily processed pharmaceuticals and food products, DNA is often fragmented and present in trace amounts.
The Innovation: We utilize high-capture spin columns featuring a modified silica topology engineered to bind micro-fragmented DNA sequences, even from acidic or high-heat environments like canning or sterilization.
The Result: Successful extraction from low-biomass samples where standard methods find nothing.
The "Smart Target" Approach
Extraction is only half the battle; specificity is the other. DNALYZE TM employs probe-based qPCR kinetics to lock onto unique genetic signatures.
Ultra-Conserved Target Regions: We target stable chromosomal DNA regions that remain intact even after aggressive industrial processing.
Zero Cross-Reactivity: Our smart target approach delivers 100% test specificity and differentiates porcine DNA from other biological species.
Inhibitor Shield Chemistry
Neutralizes complex lipids, gelatin, and processed additives that commonly block extraction and qPCR amplification.
Ultra-Capture Spin Columns
Proprietary binding matrices retain micro-fragmented DNA from cooked, acidic, and low-biomass samples.
Probe-Based qPCR Kinetics
High-fidelity probe chemistry locks onto conserved targets to eliminate cross-reactivity and deliver binary results.
Femtogram Detection Limits
Detects 0.001 pg porcine DNA with validated repeatability for ISO 17025 and Halal audit workflows.
Oils, gelatin, gummies, marshmallows, and processed meat products.
Documented workflows with clear traceability and repeatable performance.
Lyophilized kits shipped globally with ambient stability.